irrevocably
adv. 不能取消地；不能撤回地
例句
My relationships with friends have been irrevocably altered by their reactions to my illness.
由于朋友们对我的病情所做出的反应，我和他们的关系已经彻底改变了。
《柯林斯英汉双解大词典》
The events with Treya changed me deeply, profoundly, irrevocably.
和崔雅在一起的经历对我的改变浓烈，深刻，不可磨灭。
Watching Late Night Gimp Fight made me think I had irrevocably crossed a line.
在看《深夜打架的瘸子》时，让我想到我不可避免地跨过了一条线。
