As a codominant genetic marker, restriction fragment length polymorphisms, referred as RFLPs, has been widely Applied to the prenatal diagnosis of some genetic diseases.
限制性酶切片段长度多态性(RFLP)作为共显性的遗传标记,已广泛应用于遗传病的产前诊断。
Computer simulations have shown that the methods proposed can unbiasedly estimate the recombination frequency or linkage distance between a codominant marker and an interactive gene.